Ligand-gated ion channels transduce electrochemical signals in neurons and other excitable cells.Aside from canonical ligands, phospholipids are thought to bind specifically to the transmembrane domain of several ion channels.However, structural details of such lipid contacts remain elusive, partly due to limited resolution of these regions in expe
The COVID-19 pandemic has not only triggered an unprecedented global health crisis but also a global economic, trade and investment crisis.Global Trade in merchandise fall from 12% to 32% in 2020.FDI flows are projected to fall further by 30% to 40% in 2020-202.The decline in trade is a reflection, instead of a cause, of the economic contraction th
Advocacy around mass treatment for the elimination of selected Neglected Tropical Diseases (NTDs) has typically put the cost per person treated at less than US$ 0.50.Whilst useful for advocacy, the focus 220.10.38.20.02.001 on a single number misrepresents the complexity of delivering "free" donated medicines to about a billion people across the wo